{"id":1030,"date":"2023-03-19T14:31:09","date_gmt":"2023-03-19T13:31:09","guid":{"rendered":"https:\/\/www.francecoag.org\/?post_type=publications_science&#038;p=1030"},"modified":"2025-03-19T14:54:18","modified_gmt":"2025-03-19T13:54:18","slug":"determinants-of-adherence-and-consequences-of-the-transition-from-adolescence-to-adulthood-among-young-people-with-severe-haemophilia-transhemo-a-multicentric-french-national-observational-cross-se","status":"publish","type":"publications_science","link":"https:\/\/www.francecoag.org\/en\/publications_science\/determinants-of-adherence-and-consequences-of-the-transition-from-adolescence-to-adulthood-among-young-people-with-severe-haemophilia-transhemo-a-multicentric-french-national-observational-cross-se\/","title":{"rendered":"Nguyen A et al : Determinants of adherence and consequences of the transition from adolescence to adulthood among young people with severe haemophilia (TRANSHEMO): A multicentric French national observational cross-sectional study based on the FranceCoag registry"},"content":{"rendered":"<header id=\"heading\" class=\"heading\">\n<div id=\"full-view-heading\" class=\"full-view\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37572328\/\"><strong>https:\/\/pubmed.ncbi.nlm.nih.gov\/37572328\/<\/strong><\/a><\/p>\n<ul id=\"full-view-identifiers\" class=\"identifiers\">\n<li><span class=\"identifier pubmed\"><span class=\"id-label\">PMID: <\/span> <strong class=\"current-id\" title=\"PubMed ID\">37572328<\/strong> <\/span><\/li>\n<li><span class=\"identifier doi\"> <span class=\"id-label\"> DOI: <\/span> <a class=\"id-link\" href=\"https:\/\/doi.org\/10.1111\/hae.14841\" target=\"_blank\" rel=\"noopener\" data-ga-category=\"full_text\" data-ga-action=\"DOI\"> 10.1111\/hae.14841 <\/a> <\/span><\/li>\n<\/ul>\n<\/div>\n<\/header>\n<div id=\"abstract\" class=\"abstract\">\n<h2 class=\"title\">Abstract<\/h2>\n<div id=\"eng-abstract\" class=\"abstract-content selected\">\n<p><strong class=\"sub-title\"> Introduction: <\/strong> It is necessary to gain insights into adherence to healthcare in people with severe haemophilia (PwSH), especially during the transition from paediatric to adult care, which is an important phase in lives of young people with childhood chronic disease. This adherence can be considered as a marker of successful transition.<\/p>\n<p><strong class=\"sub-title\"> Objectives: <\/strong> The main objective of the quantitative phase of the TRANSHEMO project was to compare the adherence to healthcare between adolescents and young adults (YAs) with severe haemophilia. The secondary objective was to identify the determinants (facilitators and barriers) of this adherence and associations between these determinants.<\/p>\n<p><strong class=\"sub-title\"> Methods: <\/strong> A multicentre, observational, cross-sectional study was conducted in 2017-2019 on PwSH aged between 14 and 17 years (adolescents) or between 20 and 29 years (YAs), included in the FranceCoag registry and having completed the questionnaires. The adherence to healthcare (treatment regimens and clinical follow-up) was compared between adolescents and YAs using the chi-squared test. The determinants of this adherence were analysed by structural equation modelling.<\/p>\n<p><strong class=\"sub-title\"> Results: <\/strong> There were 277 participants, 107 adolescents, and 170 YAs. The rate of adolescents adhering to healthcare was 82.2%, while the rate of YAs was 61.2% (p &lt; .001). The barriers to the adherence to healthcare were being YA, having repeated at least one school grade and presenting mental health concerns.<\/p>\n<p><strong class=\"sub-title\"> Conclusion: <\/strong> Adolescents had better adherence to healthcare than YAs. According to the determinants enlightened in this project, targeted supportive strategies and adapted therapeutic education programs can be developed for young PwSH to facilitate their adherence to healthcare.<\/p>\n<\/div>\n<p><strong class=\"sub-title\"> Keywords: <\/strong> adherence; adolescents; haemophilia; quality of life; transition; young adults.<\/p>\n<\/div>\n<p id=\"copyright\" class=\"copyright\">\u00a9 2023 John Wiley &amp; Sons Ltd.<\/p>\n","protected":false},"parent":0,"template":"","keyword":[],"class_list":["post-1030","publications_science","type-publications_science","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Nguyen A et al : Determinants of adherence and consequences of the transition from adolescence to adulthood among young people with severe haemophilia (TRANSHEMO): A multicentric French national observational cross-sectional study based on the FranceCoag registry - FranceCoag<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.francecoag.org\/en\/publications_science\/determinants-of-adherence-and-consequences-of-the-transition-from-adolescence-to-adulthood-among-young-people-with-severe-haemophilia-transhemo-a-multicentric-french-national-observational-cross-se\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nguyen A et al : Determinants of adherence and consequences of the transition from adolescence to adulthood among young people with severe haemophilia (TRANSHEMO): A multicentric French national observational cross-sectional study based on the FranceCoag registry - FranceCoag\" \/>\n<meta property=\"og:description\" content=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37572328\/ PMID: 37572328 DOI: 10.1111\/hae.14841 Abstract Introduction: It is necessary to gain insights into adherence to healthcare in people with [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.francecoag.org\/en\/publications_science\/determinants-of-adherence-and-consequences-of-the-transition-from-adolescence-to-adulthood-among-young-people-with-severe-haemophilia-transhemo-a-multicentric-french-national-observational-cross-se\/\" \/>\n<meta property=\"og:site_name\" content=\"FranceCoag\" \/>\n<meta property=\"article:modified_time\" content=\"2025-03-19T13:54:18+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.francecoag.org\\\/en\\\/publications_science\\\/determinants-of-adherence-and-consequences-of-the-transition-from-adolescence-to-adulthood-among-young-people-with-severe-haemophilia-transhemo-a-multicentric-french-national-observational-cross-se\\\/\",\"url\":\"https:\\\/\\\/www.francecoag.org\\\/en\\\/publications_science\\\/determinants-of-adherence-and-consequences-of-the-transition-from-adolescence-to-adulthood-among-young-people-with-severe-haemophilia-transhemo-a-multicentric-french-national-observational-cross-se\\\/\",\"name\":\"Nguyen A et al : Determinants of adherence and consequences of the transition from adolescence to adulthood among young people with severe haemophilia (TRANSHEMO): A multicentric French national observational cross-sectional study based on the FranceCoag registry - 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